Dogs are more than just pets; they are beloved members of our families. As a dog lover, trainer, and expert, I, Aamir Iqbal, understand the importance of keeping our canine companions healthy and happy. One common health issue that affects dogs is high liver enzymes, which can impact their life expectancy. In this comprehensive guide, we’ll explore the causes of high liver enzymes, how to identify the problem, and what you can do to help your furry friend live a longer, healthier life.

liver enzymes dogs

Causes of High Liver Enzymes in Dogs

Liver enzymes are proteins that help the liver perform various functions, such as breaking down toxins and metabolizing nutrients. High liver enzyme levels can indicate a problem with the liver or other health issues. Some common causes of elevated liver enzymes in dogs include:

  1. Hepatitis: Inflammation of the liver caused by infections, toxins, or immune system disorders.
  2. Liver shunts: Abnormal blood vessels that bypass the liver, causing toxins to build up in the bloodstream.
  3. Cushing’s disease: A hormonal imbalance that results in the overproduction of cortisol, leading to liver damage.
  4. Cancer: Liver tumors, both benign and malignant, can cause increased liver enzyme levels.
  5. Infections: Bacterial, viral, or parasitic infections can cause inflammation and liver enzyme elevation.
  6. Medications: Certain drugs, such as anti-inflammatory medications or steroids, can affect liver enzyme levels.

Symptoms and Diagnosis

Identifying high liver enzymes early is crucial for effective treatment and improving your dog’s life expectancy. Some common symptoms of liver issues in dogs include:

  1. Lethargy or weakness
  2. Loss of appetite
  3. Weight loss
  4. Increased thirst and urination
  5. Jaundice (yellowing of the eyes, gums, and skin)
  6. Vomiting or diarrhea
  7. Swollen abdomen

If you notice any of these symptoms in your dog, consult your veterinarian immediately. Your vet will likely perform blood tests, such as a complete blood count (CBC) and a serum biochemistry panel, to assess liver enzyme levels. Additional diagnostic tests, such as ultrasound or liver biopsy, may be necessary to determine the underlying cause of the elevated liver enzymes.

Treatment Options

The treatment for high liver enzymes in dogs depends on the underlying cause. Some potential treatment options include:

  1. Medications: Anti-inflammatory drugs, antibiotics, or medications to manage specific conditions (e.g., drugs for Cushing’s disease) may be prescribed.
  2. Dietary changes: A veterinarian may recommend a diet low in protein and high in antioxidants, fiber, and essential nutrients to support liver function.
  3. Supplements: Nutritional supplements, such as milk thistle, SAM-e, or antioxidants, can help support liver health and function.
  4. Surgical intervention: In cases of liver shunts or tumors, surgery may be necessary to correct the issue or remove the tumor.
  5. Supportive care: Intravenous fluids, electrolyte replacement, and other supportive therapies may be needed, depending on the severity of the condition.

Prognosis and Life Expectancy

The prognosis and life expectancy for a dog with high liver enzymes depend on several factors, including the underlying cause, the dog’s overall health, and the effectiveness of the treatment. Early detection and intervention are crucial for improving the outcome.

In many cases, with proper treatment and care, dogs with high liver enzymes can live a normal and happy life. However, it’s essential to work closely with your veterinarian to monitor your dog’s liver enzyme levels and overall health.

Regular check-ups and blood tests will help ensure that any changes in your dog’s liver function are detected and addressed promptly. Your veterinarian may adjust the treatment plan as needed to provide the best possible care for your furry friend.

Preventive Measures

While it’s not always possible to prevent high liver enzymes in dogs, there are some steps you can take to help maintain your dog’s liver health:

  1. Regular veterinary care: Routine check-ups and blood work can help detect any liver issues early, improving the chances of successful treatment.
  2. Vaccinations: Keep your dog up-to-date on vaccinations to prevent liver infections, such as canine hepatitis.
  3. Balanced diet: Feed your dog a well-balanced, nutritious diet that meets their specific needs. Consult your veterinarian for dietary recommendations based on your dog’s age, breed, and health.
  4. Avoid toxins: Keep your dog away from toxic substances, such as household cleaners, pesticides, and certain plants, which can cause liver damage if ingested.
  5. Monitor medications: If your dog is on long-term medications, work with your veterinarian to monitor their liver function and adjust dosages or medications as needed.

Throughout my journey as a dog lover, trainer, and expert, I’ve encountered many personal experiences that have shaped my understanding of canine health. I’d like to share one such story that demonstrates the remarkable benefits of using a digestive enzyme supplement called Prozyme.

A Personal Experience: How Prozyme Improved My Dog’s Digestive Health

I’m not one to take the time to write many reviews, but in this case, I felt it worth the effort to share my experience with Prozyme, a digestive enzyme supplement for dogs. We have a 1 1/2-year-old English Springer Spaniel who became very ill last summer, resulting in hospitalization for several days. He was diagnosed with pancreatitis and hemorrhagic gastroenteritis, leaving both our vet and the hospital vet stupefied since he was an atypical candidate for these health issues.

After a six-day stay at the hospital, we brought our dog home, and he continued on medication for diarrhea and vomiting for another week. Our vet prescribed Hill’s Prescription Diet i/d Digestive Care Low Fat Dry Dog Food and recommended we start using Prozyme with each meal. We continued using Prozyme even after transitioning to Fromm Weight Management Gold Dog Food, a high-quality, lower-fat alternative to his original diet.

I was initially skeptical about the enzyme supplement’s potential benefits, but after two weeks of using Prozyme, we noticed a significant improvement in our dog’s stools. They became smaller, firmer, and more regular, occurring three times a day like clockwork. The successful transition to the new dog food and continued use of Prozyme has brought our dog back to health, and he is now slowly gaining weight.

I am utterly convinced that Prozyme works amazingly well. Our dog is happy and healthy once again, without the occasional “soft-serve” stools that he used to have before he got ill. I will continue to use this daily in his food forever.

Sharing this personal experience highlights the potential benefits of using a digestive enzyme supplement like Prozyme, especially for dogs with digestive issues. However, it is essential to consult with your veterinarian before starting any new supplement or treatment, as each dog’s needs may vary.


As a dog lover, trainer, and expert, I understand how important it is to keep our canine companions healthy and happy. High liver enzymes in dogs can be a cause for concern, but with early detection, proper treatment, and diligent care, many dogs can live a long and fulfilling life. By understanding the causes, symptoms, and treatment options for high liver enzymes, you can help ensure that your furry friend enjoys the best possible quality of life.

Remember, always consult your veterinarian if you have concerns about your dog’s health or notice any unusual symptoms. Working together with your vet, you can provide the best care for your beloved pet and help them live a long, happy life.

Aamir Iqbal

Aamir is crazy for pets, but not the traditional ones… In fact, he enjoys chilling with cold-blooded reptiles. He loves adding reptiles and amphibians, whom he terms as his family. His local community calls him, Amir the Beast Boy!

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